What is the protocol for treating opioid overdose?

• A. Administer naloxone only if respiratory depression is absent
• B. Treat per Opioid Overdose Protocol
• C. Treat with standard trauma protocol
• D. Avoid any medication due to risk of withdrawal

Answer: (B)

Treating an opioid overdose centers on reversing the opioid effects quickly with a protocol designed for this situation. When someone shows signs of overdose—such as slow or absent breathing, unconsciousness, or blue-tinged lips—the priority is to reverse respiratory depression and get medical help. The standard approach is to administer naloxone, an opioid antagonist, to displace the opioid from its receptors and restore breathing. If there’s no improvement after an initial dose, a second dose or additional doses may be needed, and you should continue to monitor the person and seek emergency care. Provide airway support and rescue breathing if trained, and transport to a hospital even if the person improves, because symptoms can return as the naloxone wears off.

Why this fits the question: the protocol specifically guides responders on how to handle suspected opioid overdose, focusing on rapid reversal of life-threatening respiratory depression and subsequent medical evaluation. The other options miss the central action—using an opioid reversal agent when breathing is reduced—and rely on generic or inappropriate approaches (trauma protocols or avoiding medication).